Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624559 | 0.91 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6626070 | 0.90 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6624518 | 0.89 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6624396 | 0.89 | ADORA2A (0.67) | ADORA2A | |
| SCHEMBL6623552 | 0.88 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6623523 | 0.88 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6646491 | 0.88 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6625577 | 0.87 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6626603 | 0.87 | ADORA2A (0.62) | ADORA2A | |
| SCHEMBL6624903 | 0.86 | ADORA2A (0.62) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976753-B1 | [1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-6222035-B1 | AS ADENOSINE A.SUB.2A RECEPTOR ANTAGONISTS AND ARE USEFUL FOR THERAPY OR OR PROPHYLAXIS OF VARIOUS DISEASES INDUCED BY HYPERACTIVITY OF ADENOSINE A.SUB.2A RECEPTORS SUCH AS PARKINSON'S DISEASE, SENILE DEMENTIA OR DEPRESSION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0976753-A1 | [1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |