Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310504 | 1.00 | CHRNA7 (0.55) | CHRNA7NAAAKMT2AMEN1GRM5 | |
| SCHEMBL6310510 | 1.00 | CHRNA7 (0.55) | CHRNA7NAAAKMT2AMEN1GRM5 | |
| SCHEMBL6310757 | 0.95 | CHRNA7 (0.48) | CHRNA7NAAAKMT2AMEN1GRM5 | |
| SCHEMBL6305841 | 0.90 | CHRNA7 (0.57) | CHRNA7KMT2AMEN1L3MBTL1USP30 | |
| SCHEMBL6305844 | 0.90 | CHRNA7 (0.57) | CHRNA7KMT2AMEN1L3MBTL1USP30 | |
| SCHEMBL6631814 | 0.90 | CHRNA7 (0.57) | CHRNA7KMT2AMEN1L3MBTL1USP30 | |
| SCHEMBL6305055 | 0.87 | CHRNA7 (0.65) | CHRNA7KMT2AMEN1GRM5USP30 | |
| SCHEMBL6632056 | 0.87 | CHRNA7 (0.65) | CHRNA7KMT2AMEN1GRM5USP30 | |
| SCHEMBL6305052 | 0.87 | CHRNA7 (0.65) | CHRNA7KMT2AMEN1GRM5USP30 | |
| SCHEMBL6303021 | 0.86 | CHRNA7 (0.66) | CHRNA7NAAAKMT2AMEN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480977-A2 | SUBSTITUTED ARYL COMPOUNDS FOR TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-01 | — | — | EP | claimed |
| WO-2003070728-A2 | AZABICYCLO-SUBSTITUTED BENZOYLAMIDES AND THIOAMIDES FOR TREATMENT OF CNS-RELATED DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | claimed |