Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6507572 | 0.99 | NPSR1 (0.42) | NPSR1KDM4EMEN1GAAMAPT | |
| SCHEMBL7257145 | 0.82 | KCNH2 (0.37) | NPSR1MEN1MAPTMAPK1KMT2A | |
| SCHEMBL6632841 | 0.80 | MEN1 (0.44) | NPSR1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6630805 | 0.79 | PARP1 (0.43) | KDM4EMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6502264 | 0.79 | MEN1 (0.43) | NPSR1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6630043 | 0.79 | PARP1 (0.38) | KDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6510200 | 0.78 | PARP1 (0.42) | KDM4EMAPK1ALDH1A1 | |
| SCHEMBL6509219 | 0.78 | GAA (0.41) | NPSR1KDM4EMEN1GAAMAPT | |
| Hydrochloric Acid SCHEMBL6503053 | 0.78 | PARP1 (0.38) | KDM4EMAPTALDH1A1 | |
| SCHEMBL6630480 | 0.78 | MAPT (0.40) | NPSR1KDM4EMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309594-B1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2004-12-15 | — | — | EP | claimed |
| EP-1309594-B1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2004-12-15 | — | — | EP | disclosed |
| EP-1309594-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012239-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2002-02-14 | — | — | WO | disclosed |