Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881547 | 0.80 | CTNNB1 (0.48) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL6630801 | 0.76 | CTNNB1 (0.57) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL7693879 | 0.76 | CTNNB1 (0.77) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL4879222 | 0.74 | CTNNB1 (0.42) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL29946580 | 0.73 | CTNNB1 (0.67) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL6633359 | 0.73 | CTNNB1 (0.53) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL6630926 | 0.72 | CTNNB1 (0.51) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL17397069 | 0.71 | CTNNB1 (0.74) | CTNNB1IRAK4PARP1MAPTMEN1 | |
| SCHEMBL1702138 | 0.71 | CTNNB1 (0.68) | CTNNB1IRAK4LMNAHTTKDM4E | |
| SCHEMBL30060692 | 0.71 | CTNNB1 (0.68) | CTNNB1IRAK4LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480977-A2 | SUBSTITUTED ARYL COMPOUNDS FOR TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-01 | — | — | EP | claimed |
| WO-2003070728-A2 | AZABICYCLO-SUBSTITUTED BENZOYLAMIDES AND THIOAMIDES FOR TREATMENT OF CNS-RELATED DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | claimed |