Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938146 | 0.92 | NOTUM (0.60) | NPY5RNOTUMRPS6KB1GPR119FFAR4 | |
| SCHEMBL3938151 | 0.92 | NOTUM (0.60) | NPY5RNOTUMRPS6KB1GPR119FFAR4 | |
| SCHEMBL17846438 | 0.82 | EPHX2 (0.58) | NPY5RNOTUMGPR119DRD2DRD3 | |
| SCHEMBL31381256 | 0.81 | NOTUM (0.68) | NOTUMRPS6KB1GPR119FFAR4ADRB1 | |
| SCHEMBL19711007 | 0.80 | NOTUM (0.61) | NPY5RNOTUMGPR119GFER | |
| SCHEMBL2558104 | 0.78 | NOTUM (0.56) | NPY5RNOTUMRPS6KB1GPR119FFAR4 | |
| SCHEMBL316060 | 0.78 | CA12 (0.57) | NPY5RNOTUMGPR119DRD2DRD3 | |
| SCHEMBL5800964 | 0.77 | NOTUM (0.83) | NOTUMGPR119FFAR4ADRB1RAB9A | |
| SCHEMBL13722253 | 0.76 | NOTUM (0.64) | NPY5RNOTUMGPR119FFAR4ADRB1 | |
| SCHEMBL23731860 | 0.76 | NOTUM (0.59) | NPY5RNOTUMGPR119FFAR4ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417202-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |