Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.65 |
| ▸ | CTSS | P25774 | 14/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062350 | 1.00 | CTSC (0.65) | CTSCCTSSCTSBCTSLCTSK | |
| SCHEMBL6630445 | 1.00 | CTSC (0.65) | CTSCCTSSCTSBCTSLCTSK | |
| SCHEMBL6063126 | 0.81 | CTSC (0.67) | CTSCCTSSCTSBCTSL | |
| SCHEMBL6063121 | 0.81 | CTSC (0.67) | CTSCCTSSCTSBCTSL | |
| SCHEMBL6061898 | 0.81 | CTSC (0.67) | CTSCCTSSCTSBCTSL | |
| SCHEMBL6627501 | 0.81 | CTSC (0.67) | CTSCCTSSCTSBCTSL | |
| SCHEMBL7649115 | 0.80 | CTSC (0.66) | CTSCCTSSCTSBCTSL | |
| SCHEMBL6062237 | 0.80 | CTSC (0.66) | CTSCCTSSCTSBCTSLCTSF | |
| SCHEMBL6630078 | 0.80 | CTSC (0.66) | CTSCCTSSCTSBCTSLCTSF | |
| SCHEMBL6630308 | 0.80 | CTSC (0.66) | CTSCCTSSCTSBCTSLCTSF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | claimed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | claimed |
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |