Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.71 |
| ▸ | MAOA | P21397 | 3/20 | 0.71 |
| ▸ | F10 | P00742 | 13/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | CALML3 | P27482 | 1/20 | 0.57 |
| ▸ | SDHA | P31040 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157596 | 1.00 | MAOB (0.71) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL6040534 | 0.97 | MAOB (0.75) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL6040527 | 0.97 | MAOB (0.75) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL6040229 | 0.91 | MAOB (0.80) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL6040231 | 0.91 | MAOB (0.80) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL7157536 | 0.90 | MAOB (0.73) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL7161238 | 0.90 | MAOB (0.73) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL7154461 | 0.90 | MAOB (0.74) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL7154465 | 0.90 | MAOB (0.74) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL7158485 | 0.89 | MAOB (0.56) | MAOBMAOAF10LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6537986-B2 | With thiourea, thioamide, or dithiocarbamate functionality; (S)-N-(((3-(3-fluoro-4-morpholinyl)phenyl)-2-oxo-5 -oxazolidinyl)methyl)thioacetamide for example; treats multiple-resistant staphylococci | PHARMACIA & UPJOHN COMPANY | 2003-03-25 | — | — | US | claimed |
| EP-1451164-A2 | AMIDE DERIVATIVES HAVING IMPROVED SOLUBILITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003006440-A2 | AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |