Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28410474 | 0.88 | — | — | |
| SCHEMBL7994821 | 0.78 | — | — | |
| SCHEMBL19259380 | 0.73 | USP2 (0.38) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL19259367 | 0.73 | USP2 (0.38) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL7992357 | 0.72 | — | — | |
| SCHEMBL7754897 | 0.72 | — | — | |
| SCHEMBL7992425 | 0.71 | — | — | |
| SCHEMBL18196874 | 0.71 | — | — | |
| SCHEMBL8244611 | 0.71 | — | — | |
| SCHEMBL13246524 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567692-A | CONTROLLING BACTERIA INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1996-10-22 | — | — | US | claimed |
| US-5442059-A | Antibiotics for mammalian and veterninary diseases | AMERICAN CYANAMID COMPANY (US) | 1995-08-15 | — | — | US | claimed |
| US-5371076-A | ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| EP-1435352-A2 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | Wyeth Holdings Corporation (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-0582829-B1 | 9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines as antibiotic agents | AMERICAN CYANAMID CO (US) | 2001-09-12 | — | — | EP | disclosed |
| US-5639742-A | ANTIBIOTIC; BACTERICIDE | LEE VING JICK (US) | 1997-06-17 | — | — | US | disclosed |
| US-5567692-A | CONTROLLING BACTERIA INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| US-5495030-A | CHEMICAL INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1996-02-27 | — | — | US | disclosed |
| US-5442059-A | Antibiotics for mammalian and veterninary diseases | AMERICAN CYANAMID COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| US-5371076-A | ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0618190-A1 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0582829-A1 | 9-(substituted glycyl) amido - 6-demethyl-6-deoxytetracyclines as antibiotic agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | disclosed |