Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657666 | 0.78 | HTR2C (0.62) | MAPTHSD17B10KDRKMT2AMEN1 | |
| SCHEMBL38660646 | 0.77 | KMT2A (0.58) | MAPTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL29237790 | 0.77 | KMT2A (0.58) | MAPTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL10439987 | 0.76 | HSD17B10 (0.46) | HSD17B10KDRKMT2AMEN1RIPK2 | |
| SCHEMBL13434056 | 0.75 | PTPN1 (0.51) | MAPTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL30511914 | 0.75 | PTPN1 (0.51) | MAPTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL2309532 | 0.74 | CYP1A2 (0.45) | KDRPTPN1PTPN11 | |
| SCHEMBL7837169 | 0.73 | PTPN1 (0.61) | HSD17B10KDRKMT2AMEN1RAB9A | |
| SCHEMBL9523753 | 0.73 | KMT2A (0.43) | MAPTHSD17B10KDRKMT2AMEN1 | |
| SCHEMBL10440111 | 0.72 | TYMS (0.46) | MAPTKMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |