⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634121 | 0.90 | — | — | |
| SCHEMBL7484929 | 0.90 | — | — | |
| SCHEMBL6631513 | 0.87 | MEN1 (0.43) | — | |
| SCHEMBL6632676 | 0.86 | KCNH2 (0.44) | — | |
| SCHEMBL6632748 | 0.85 | KCNH2 (0.44) | — | |
| SCHEMBL6633072 | 0.83 | MEN1 (0.47) | — | |
| SCHEMBL6633221 | 0.82 | MEN1 (0.42) | — | |
| SCHEMBL6634659 | 0.82 | MEN1 (0.47) | — | |
| SCHEMBL6659286 | 0.81 | KCNH2 (0.67) | — | |
| SCHEMBL6362900 | 0.79 | KCNH2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421089-A1 | 4-THIOXO-4,7-DIHYDRO-THIENO 2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | Pharmacia & Upjohn Company (US) | 2004-05-26 | — | — | EP | claimed |
| US-6620810-B2 | Treating a herpesvirus infection, atherosclerosis or restenosis | PHARMACIA & UPJOHN COMPANY | 2003-09-16 | — | — | US | claimed |
| WO-2003020729-A1 | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANT IVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-03-13 | — | — | WO | claimed |