SCHEMBL6633673

SCHEMBL6633673

Cc1c(CN(C)CC(O)c2cccnc2O)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6316675 0.90 KCNH2 (0.77) KCNH2
SCHEMBL6316707 0.90 KCNH2 (0.77) KCNH2
SCHEMBL6325645 0.88 KCNH2 (0.74) KCNH2
SCHEMBL6323702 0.88 KCNH2 (0.74) KCNH2
SCHEMBL6327127 0.88 KCNH2 (0.74) KCNH2
SCHEMBL6319528 0.86 KCNH2 (0.77) KCNH2
SCHEMBL6317586 0.86 KCNH2 (0.84) KCNH2
SCHEMBL6318883 0.86 KCNH2 (0.87) KCNH2
SCHEMBL6320779 0.85 KCNH2 (0.74) KCNH2
SCHEMBL6325902 0.85 KCNH2 (1.00) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472260-A2 THIENO(3,2-B)PYRIDONES AS ANTIVIRAL COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 2004-11-03 EP disclosed
WO-2003059878-A2 THIENO (3, 2-B) PYRIDONES AS ANTIVIRAL COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 2003-07-24 WO disclosed