Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2213092 | 1.00 | HRH3 (0.45) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2208289 | 0.99 | PDE3B (0.45) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| SCHEMBL12511629 | 0.94 | UTS2R (0.48) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2214526 | 0.94 | AR (0.45) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2210097 | 0.93 | PDE3B (0.45) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2212560 | 0.93 | UTS2R (0.44) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2211174 | 0.91 | PDE3B (0.42) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2213021 | 0.91 | UTS2R (0.43) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2214070 | 0.90 | UTS2R (0.43) | HRH3PDE3BPDE3ASIGMAR1UTS2R | |
| Trifluoroacetic Acid SCHEMBL2213098 | 0.90 | UTS2R (0.44) | HRH3SIGMAR1UTS2RCCR3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389616-A1 | NOVEL BENZYLPIPERIDINE COMPOUND | Mitsubishi Pharma Corporation (JP) | 2004-02-18 | — | — | EP | disclosed |