Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.58 |
| ▸ | MAPK13 | O15264 | 14/20 | 0.58 |
| ▸ | MAPK12 | P53778 | 14/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 14/20 | 0.58 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094765 | 0.83 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6632888 | 0.82 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11ATAD2 | |
| SCHEMBL6096253 | 0.82 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11SIRT2 | |
| SCHEMBL6094353 | 0.81 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11ATAD2 | |
| SCHEMBL6094197 | 0.80 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11DDB1 | |
| SCHEMBL6093762 | 0.80 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11SIRT2 | |
| SCHEMBL6096703 | 0.79 | MAPK14 (0.63) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5172447 | 0.79 | MAPK14 (0.79) | MAPK14MAPK13MAPK12MAPK11AVPR2 | |
| SCHEMBL6097137 | 0.78 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11SIRT2 | |
| SCHEMBL6094908 | 0.78 | MAPK14 (0.77) | MAPK14MAPK13MAPK12MAPK11AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423356-A2 | NOVEL AMINOBENZOEPHENONES | Leo Pharma A/S (DK) | 2004-06-02 | — | — | EP | claimed |
| WO-2003018535-A2 | NOVEL AMINOBENZOEPHENONES | LEO PHARMA A/S (DK) | 2003-03-06 | — | — | WO | claimed |
| EP-1423356-A2 | NOVEL AMINOBENZOEPHENONES | Leo Pharma A/S (DK) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003018535-A2 | NOVEL AMINOBENZOEPHENONES | LEO PHARMA A/S (DK) | 2003-03-06 | — | — | WO | disclosed |