SCHEMBL663384

SCHEMBL663384

CC(C)C1CCC(C)(C(=O)O)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.54
MAPK1 P28482 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
TP53 P04637 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
THPO P40225 1/20 0.34
STAT6 P42226 1/20 0.34
HIF1A Q16665 1/20 0.34
NPC1 O15118 1/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
MTOR P42345 1/20 0.34
RAB9A P51151 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
OPRL1 P41146 3/20 0.34
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2701836 1.00 FFAR3 (0.54) FFAR3MAPK1NPSR1TP53NFKB1
Fluoride SCHEMBL10012083 0.98 FFAR3 (0.52) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL6064720 0.88 FFAR3 (0.44) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL3191376 0.88 FFAR3 (0.44) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL3191388 0.88 FFAR3 (0.44) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL3187205 0.88 FFAR3 (0.44) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL6064722 0.88 FFAR3 (0.44) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL4539886 0.88 FFAR3 (0.44) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL25287762 0.81 FFAR3 (0.52) FFAR3MAPK1NPSR1TP53NFKB1
SCHEMBL10012078 0.81 FFAR3 (0.31) FFAR3OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930456-A Method for preparing N-ethyl-L-menthyl formamide by continuous flow technology 安徽科芯微流化工科技有限公司 2025-05-06 CN claimed
CN-117304070-A Synthesis method of cyclohexanamide cooling agent 安徽华业香料合肥有限公司 2023-12-29 CN claimed
CN-114381749-A Method for synthesizing menthyl formic acid 万华化学集团股份有限公司 2022-04-22 CN claimed
US-20260014103-A1 COMBINATION REMEDY SYMRISE AG (DE) 2026-01-15 US disclosed
CN-119930456-A Method for preparing N-ethyl-L-menthyl formamide by continuous flow technology 安徽科芯微流化工科技有限公司 2025-05-06 CN disclosed
CN-119080629-A Menthol amide cooling agent WS-5 and preparation method thereof 辽宁友之泰医药科技有限公司 2024-12-06 CN disclosed
CN-119039169-A Preparation method of cooling agent WS-3 辽宁友之泰医药科技有限公司 2024-11-29 CN disclosed
CN-115806481-B Separation and purification method of L-menthyl formic acid 安徽丰乐香料有限责任公司 2024-11-22 CN disclosed
CN-108367178-B Composition with stable taste and smell 西姆莱斯股份公司 2024-09-27 CN disclosed
CN-118666665-A Automatic continuous production method for menthyl carboxylic acid format reaction 河南华龙香料有限公司 2024-09-20 CN disclosed
CN-118141701-A Composition containing benzoic acid derivative or furoic acid derivative and use of the derivative for emulsion and foam stability 西姆莱斯股份公司 2024-06-07 CN disclosed
US-4797146-A INSECTICIDES, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-01-10 US disclosed
US-4797502-A ENZYME INHIBITORS, ANTILIPEMIC AGENTS TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1989-01-10 US disclosed
EP-0243868-A2 Pyridylthio-acylanilides BAYER AG (DE) 1987-11-04 EP disclosed
EP-0226885-A1 Pyrimidylmercapto-acylanilides BAYER AG (DE) 1987-07-01 EP disclosed
US-4675428-A Sulfonic acid ester derivatives useful as antilipemic agents TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1987-06-23 US disclosed
EP-0117876-B1 SULFONIC ESTER DERIVATIVES AND PROCESS FOR THEIR PREPARATION TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1986-12-10 EP disclosed
US-4627871-A Herbicidal 2-[4-substituted carboxyamino-phenoxy (or phenyl mercapto)]-substituted pyrimidines BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
EP-0168608-A2 Substituted carboxylic-acid anilides BAYER AG (DE) 1986-01-22 EP disclosed
EP-0117876-A1 SULFONIC ESTER DERIVATIVES AND PROCESS FOR THEIR PREPARATION TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1984-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014103-A1 COMBINATION REMEDY TAS2R43, TAS2R41, TAS2R60 FFAR3 354/4885MAPK1 3038/4885NPSR1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.