Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL11219192 | 0.98 | TSHR (0.55) | TSHRLMNAALOX12ACHEHTT | |
| Decane SCHEMBL7111192 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Heptane SCHEMBL7745742 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Hexadecane SCHEMBL4950420 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Dodecane SCHEMBL4946383 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Heptane SCHEMBL16466974 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Decane SCHEMBL7261270 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Octane SCHEMBL11193559 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Heptane SCHEMBL6664964 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT | |
| Heptane SCHEMBL11509356 | 0.93 | TSHR (0.61) | TSHRLMNAALOX12ACHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036077-B1 | PHOTOCHROMIC PYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2004-02-04 | — | — | EP | disclosed |
| US-6106744-A | HAVING A SUBSTITUTED OR UNSUBSTITUTED ?S? PYRAN RING, THE 3,4 POSITIONS OF WHICH ARE FUSED TO THE F SIDE OF THE NAPHTHO PORTION OF THE NAPHTHOPYRAN, AND CERTAIN SUBSTITUENTS AT THE 2-POSITION OF THE ?T? PYRAN RING. | PPG INDUSTRIES OHIO, INC. (US) | 2000-08-22 | — | — | US | disclosed |