Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490793 | 0.84 | BCHE (0.60) | BCHEBACE1 | |
| SCHEMBL3490792 | 0.84 | BCHE (0.60) | BCHEBACE1 | |
| SCHEMBL6636732 | 0.74 | POLB (0.50) | BCHEPOLBKDM4ABACE1MEN1 | |
| SCHEMBL3491060 | 0.72 | BCHE (0.54) | BCHEBACE1 | |
| SCHEMBL3491064 | 0.72 | BCHE (0.54) | BCHEBACE1 | |
| SCHEMBL3491799 | 0.71 | BCHE (0.53) | BCHEPOLBBACE1 | |
| SCHEMBL3491797 | 0.71 | BCHE (0.53) | BCHEPOLBBACE1 | |
| SCHEMBL3490810 | 0.71 | BACE1 (0.65) | BCHEBACE1 | |
| SCHEMBL3490808 | 0.71 | BACE1 (0.65) | BCHEBACE1 | |
| SCHEMBL3489233 | 0.68 | BCHE (0.49) | BCHEPOLBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409450-A1 | N-(3-AMINO-2-HYDROXY-PROPYL) SUBSTITUTED ALKYLAMIDE COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 2004-04-21 | — | — | EP | claimed |
| WO-2003006423-A1 | N-(3-AMINO-2-HYDROXY-PROPYL) SUBSTITUTED ALKYLAMIDE COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | claimed |