Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634847 | 1.00 | MAPT (0.57) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6634094 | 0.86 | F2 (0.56) | ALDH1A1KMT2AMEN1TDP1RRM1 | |
| SCHEMBL6634091 | 0.86 | F2 (0.56) | ALDH1A1KMT2AMEN1TDP1RRM1 | |
| SCHEMBL6635107 | 0.84 | F2 (0.55) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6635104 | 0.84 | F2 (0.55) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6635410 | 0.84 | MEN1 (0.56) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6635407 | 0.84 | MEN1 (0.56) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6635726 | 0.78 | MAPT (0.74) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6635725 | 0.78 | MAPT (0.74) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6633122 | 0.77 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |