Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28789930 | 0.97 | TSHR (0.67) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL1453986 | 0.94 | — | — | |
| SCHEMBL27740814 | 0.89 | TSHR (0.79) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL1279371 | 0.86 | TSHR (0.84) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL20526061 | 0.86 | TSHR (0.84) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL9614292 | 0.86 | TSHR (0.84) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL9576903 | 0.86 | TSHR (0.84) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL4370743 | 0.86 | TSHR (0.84) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL5506099 | 0.86 | TSHR (0.84) | TSHRALDH1A1ABCC4MAPT | |
| SCHEMBL11790787 | 0.86 | TSHR (0.84) | TSHRALDH1A1ABCC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061076-B1 | N-ACYL CYCLIC AMINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-12-08 | — | — | EP | disclosed |
| EP-1061076-A1 | N-ACYL CYCLIC AMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-20 | — | — | EP | disclosed |