Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.62 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.43 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634330 | 0.90 | F2 (0.51) | F2F10SMN1; SMN2PLGNQO2 | |
| Hydrochloric Acid SCHEMBL8026639 | 0.85 | F2 (0.71) | F2F10SLC22A2PLGPLAT | |
| Hydrochloric Acid SCHEMBL6780427 | 0.83 | F2 (0.67) | F2F10SLC22A2PLGPLAT | |
| SCHEMBL6634321 | 0.80 | F2 (0.85) | F2F10SLC22A2PLGPLAT | |
| SCHEMBL6637410 | 0.78 | KLK5 (0.52) | F2SMN1; SMN2 | |
| SCHEMBL6636175 | 0.78 | ITK (0.46) | F2F10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6778114 | 0.77 | NQO2 (0.56) | F2F10SLC22A2PLGPLAT | |
| Hydrochloric Acid SCHEMBL8028121 | 0.77 | F2 (0.83) | F2F10SLC22A2PLGPLAT | |
| SCHEMBL6636298 | 0.77 | F2 (0.79) | F2F10SLC22A2PLGPLAT | |
| Hydrochloric Acid SCHEMBL6780934 | 0.76 | F2 (0.98) | F2F10SLC22A2PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-06-09 | — | — | EP | disclosed |