SCHEMBL6635265

SCHEMBL6635265

CCCCCNNCCCC

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
ALDH1A1 P00352 1/20 0.59
EPHX1 P07099 8/20 0.53
ADH1B P00325 2/20 0.48
ADH1C P00326 2/20 0.48
ADH1A P07327 2/20 0.48
ADH7 P40394 2/20 0.48
THRB P10828 1/20 0.47
ADH4 P08319 1/20 0.46
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
PPARA Q07869 2/20 0.40
LMNA P02545 1/20 0.40
GBA1 P04062 1/20 0.39
CASP2 P42575 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10351826 0.97 EPHX1 (0.58) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL18265354 0.97 EPHX1 (0.58) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL10566383 0.97 EPHX1 (0.58) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL27725955 0.97 EPHX1 (0.58) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL88378 0.96 TSHR (0.62) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL23270896 0.93 EPHX1 (0.61) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL16333588 0.93 EPHX1 (0.53) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL8416435 0.93 EPHX1 (0.61) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL8419933 0.93 EPHX1 (0.61) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL1795309 0.93 EPHX1 (0.61) TSHRALDH1A1EPHX1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369181-A Process for treating proliferative skin diseases using certain 6,8-substituted ribofuranosylpurine-3',5'-cyclic phosphates SRI INTERNATIONAL (US) 1983-01-18 US claimed
US-10973466-B2 System for determining airway patency FISHER & PAYKEL HEALTHCARE LIMITED (NZ) 2021-04-13 US disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed