Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 8/20 | 0.40 |
| ▸ | FNTB | P49356 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500364 | 0.90 | TSHR (0.48) | TSHRHPGDNPC1FNTAFNTB | |
| SCHEMBL3499967 | 0.89 | FNTA (0.52) | TSHRHPGDNPC1FNTAFNTB | |
| SCHEMBL3501162 | 0.85 | FNTA (0.56) | FNTAFNTBMEN1KMT2APOLB | |
| SCHEMBL3499493 | 0.80 | FNTA (0.49) | TSHRHPGDFNTAFNTBALDH1A1 | |
| SCHEMBL3502482 | 0.79 | FNTA (0.52) | TSHRFNTAFNTBMEN1KMT2A | |
| SCHEMBL3502205 | 0.78 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL3502162 | 0.78 | FNTA (0.50) | TSHRHPGDFNTAFNTBPOLB | |
| SCHEMBL3499635 | 0.78 | FNTA (0.57) | FNTAFNTBLMNAALDH1A1 | |
| SCHEMBL3499836 | 0.78 | FNTA (0.57) | FNTAFNTBMEN1KMT2ALMNA | |
| SCHEMBL3501377 | 0.76 | FNTA (0.57) | FNTAFNTBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |