Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.65 |
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516923 | 0.90 | PPARD (0.80) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5514539 | 0.84 | PPARD (0.65) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5510557 | 0.81 | PPARD (0.82) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6236634 | 0.79 | PPARD (1.00) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5518655 | 0.79 | PPARD (0.79) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5519930 | 0.78 | PPARD (0.83) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5516731 | 0.78 | PPARD (0.64) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5526106 | 0.78 | PPARD (0.81) | PPARDPPARAPPARG | |
| SCHEMBL5512102 | 0.77 | PPARD (0.76) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6109467 | 0.77 | PPARD (0.66) | PPARDFFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480642-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072102-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |