Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615989 | 1.00 | FNTA (0.39) | FNTAFNTBABCB1HSD17B3METAP2 | |
| SCHEMBL6634139 | 0.84 | FNTA (0.45) | FNTAFNTBABCB1HSD17B3 | |
| SCHEMBL6633403 | 0.84 | FNTA (0.45) | FNTAFNTBABCB1HSD17B3 | |
| SCHEMBL6617952 | 0.81 | FNTA (0.46) | FNTAFNTBABCB1HSD17B3DAGLB | |
| SCHEMBL6632636 | 0.78 | FNTA (0.56) | FNTAFNTBABCB1HSD17B3 | |
| SCHEMBL3501311 | 0.77 | FNTA (0.50) | FNTAFNTBGRM2 | |
| SCHEMBL3501316 | 0.77 | FNTA (0.50) | FNTAFNTBGRM2 | |
| SCHEMBL7687860 | 0.77 | MEN1 (0.55) | METAP2GRM2SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL6618481 | 0.77 | MEN1 (0.55) | METAP2GRM2SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL6630439 | 0.72 | FNTA (0.44) | FNTAFNTBABCB1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |