Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.52 |
| ▸ | BCHE | P06276 | 5/20 | 0.52 |
| ▸ | ACHE | P22303 | 5/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634888 | 0.84 | DRD4 (0.48) | SCN8ACHRM2 | |
| SCHEMBL6639679 | 0.83 | CHRM2 (0.46) | CHRM2BCHERECQLTP53CYP3A4 | |
| SCHEMBL920242 | 0.79 | IDO1 (0.49) | CHRM2BCHECHRM1MEN1MAPT | |
| SCHEMBL6635774 | 0.79 | SCN8A (0.53) | SCN8ACHRM2BCHEMEN1KMT2A | |
| SCHEMBL6635360 | 0.78 | DRD4 (0.71) | SCN8AMEN1KMT2ATDP1 | |
| SCHEMBL6636607 | 0.77 | SCN8A (0.58) | SCN8ACHRM2BCHEMEN1KMT2A | |
| SCHEMBL31030404 | 0.76 | CHRM2 (0.70) | SCN8ACHRM2BCHEACHECHRM4 | |
| SCHEMBL6637667 | 0.75 | CYP1A2 (0.56) | CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4918396 | 0.75 | CHRM2 (0.79) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL7019049 | 0.75 | DRD4 (0.47) | CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165557-B1 | ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS | NEUROGEN CORP (US) | 2004-09-29 | — | — | EP | claimed |
| EP-1165557-B1 | ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS | NEUROGEN CORP (US) | 2004-09-29 | — | — | EP | disclosed |