Methylpyrrolidone

Methylpyrrolidone

SCHEMBL6635657

CN1CCCC1=O.O=C1CCCC1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.81
BRD2 P25440 1/20 0.81
TRIM24 O15164 2/20 0.48
TRIM33 Q9UPN9 2/20 0.48
ALDH1A1 P00352 3/20 0.46
INMT O95050 2/20 0.41
PIK3CD O00329 1/20 0.38
ACHE P22303 1/20 0.37
GAA P10253 4/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
PSMD14 O00487 2/20 0.36
RAB9A P51151 2/20 0.36
LMNA P02545 2/20 0.34
USP2 O75604 1/20 0.33
IDE P14735 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL8829524 0.98 BRD4 (0.77) BRD4BRD2TRIM24TRIM33ALDH1A1
Methylpyrrolidone SCHEMBL27709546 0.94 BRD4 (0.71) BRD4BRD2TRIM24TRIM33ALDH1A1
Methylpyrrolidone SCHEMBL27960874 0.93
Methylpyrrolidone SCHEMBL5477387 0.92 BRD4 (0.68) BRD4BRD2TRIM24TRIM33ALDH1A1
Methylpyrrolidone SCHEMBL8055062 0.90 BRD4 (1.00) BRD4BRD2ALDH1A1INMTPIK3CD
Methylpyrrolidone SCHEMBL487 0.90
Methylpyrrolidone SCHEMBL5423326 0.90
Methylpyrrolidone SCHEMBL1255511 0.90 BRD4 (1.00) BRD4BRD2ALDH1A1INMTPIK3CD
Methylpyrrolidone SCHEMBL9016057 0.88 BRD4 (0.85) BRD4BRD2ALDH1A1INMTPIK3CD
Methylpyrrolidone SCHEMBL25409888 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112859-B1 Donor element for laser-induced thermal transfer EASTMAN KODAK CO (US) 2004-05-19 EP disclosed
EP-1151872-A2 Donor element for laser-induced image transfer EASTMAN KODAK COMPANY (US) 2001-11-07 EP disclosed
EP-1112859-A2 Donor element for laser-induced thermal transfer EASTMAN KODAK COMPANY (US) 2001-07-04 EP disclosed
US-6190827-B1 A LASER-INDUCED WHITE TRANSFER IMAGE. EASTMAN KODAK COMPANY 2001-02-20 US disclosed
US-6165671-A Laser donor element EASTMAN KODAK COMPANY (US) 2000-12-26 US disclosed