Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.59 |
| ▸ | PPARA | Q07869 | 12/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859322 | 0.93 | PPARD (0.67) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6622885 | 0.93 | PPARD (0.68) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6637432 | 0.86 | PPARD (0.58) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6634120 | 0.81 | PPARD (0.69) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6621077 | 0.81 | PPARD (0.71) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6621320 | 0.78 | PPARD (0.67) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6621291 | 0.78 | PPARD (0.69) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6623154 | 0.78 | PPARD (0.67) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL6858900 | 0.78 | PPARD (0.67) | PPARDPPARAPPARGFFAR1MEN1 | |
| SCHEMBL4676281 | 0.77 | PPARD (0.79) | PPARDPPARAPPARGFFAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485091-A1 | THIAZOLE AND OXAZOLE DERIVATIVES THAT MODULATE PPAR ACTIVITY | Warner-Lambert Company LLC (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003074052-A1 | THIAZOLE AND OXAZOLE DERIVATIVES THAT MODULATE PPAR ACTIVITY | WARNER-LAMBERT COMPANY LLC (US) | 2003-09-12 | — | — | WO | disclosed |