Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636019 | 1.00 | NR1H2 (0.57) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL17310854 | 0.95 | NR1H2 (0.56) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL12877735 | 0.95 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL12620811 | 0.95 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL16963312 | 0.95 | NR1H2 (0.56) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL16080212 | 0.92 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL13052105 | 0.88 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL19819953 | 0.86 | NR1H2 (0.48) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL1277182 | 0.86 | NR1H2 (0.61) | NR1H2USP2SMN1; SMN2PDE4BNAMPT | |
| SCHEMBL1014216 | 0.85 | NR1H2 (0.65) | NR1H2USP2SMN1; SMN2PDE4BNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061076-B1 | N-ACYL CYCLIC AMINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-12-08 | — | — | EP | disclosed |
| EP-1061076-A1 | N-ACYL CYCLIC AMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-6140333-A | FOR TREATMENT AND/OR PROPHYLAXIS OF DISEASES INCLUDE SUCH RESPIRATORY DISEASES AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CHRONIC BRONCHITIS, ASTHMA, CHRONIC RESPIRATORY OBSTRUCTION, PULMONARY FIBROSIS, PULMONARY EMPHYSEMA | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-10-31 | — | — | US | disclosed |