SCHEMBL6636079

SCHEMBL6636079

CN(C=O)NC(=N)N1CCC(CC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.76
FNTB P49356 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6639913 0.88 FNTA (0.74) FNTAFNTB
SCHEMBL6638946 0.88 FNTA (0.75) FNTAFNTB
SCHEMBL6636021 0.88 FNTA (0.75) FNTAFNTB
SCHEMBL6637425 0.87 FNTA (0.77) FNTAFNTB
SCHEMBL6765636 0.87 FNTA (1.00) FNTAFNTB
SCHEMBL6641696 0.86 FNTA (0.76) FNTAFNTB
SCHEMBL6638255 0.86 FNTA (0.77) FNTAFNTB
SCHEMBL6638181 0.85 FNTA (0.85) FNTAFNTB
SCHEMBL6633525 0.85 FNTA (0.78) FNTAFNTB
SCHEMBL6635926 0.85 FNTA (0.73) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934303-B1 COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE SCHERING CORP (US) 2004-12-29 EP disclosed