Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.51 |
| ▸ | FNTB | P49356 | 20/20 | 0.51 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499905 | 1.00 | FNTA (0.51) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3500165 | 0.93 | FNTA (0.52) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3498228 | 0.92 | FNTA (0.53) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3498230 | 0.88 | FNTA (0.54) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499338 | 0.84 | FNTA (0.72) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499345 | 0.84 | FNTA (0.72) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499294 | 0.82 | FNTA (0.51) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499831 | 0.82 | FNTA (0.51) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3500661 | 0.82 | FNTA (0.51) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499293 | 0.82 | FNTA (0.51) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | claimed |