Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642251 | 0.90 | EDNRB (0.82) | EDNRBEDNRA | |
| SCHEMBL6641360 | 0.90 | EDNRB (0.82) | EDNRBEDNRA | |
| SCHEMBL6638424 | 0.88 | EDNRB (0.79) | EDNRBEDNRA | |
| SCHEMBL6639823 | 0.88 | EDNRB (0.79) | EDNRBEDNRA | |
| SCHEMBL6644358 | 0.87 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL6643125 | 0.87 | EDNRB (0.77) | EDNRBEDNRA | |
| SCHEMBL6646497 | 0.87 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL6644730 | 0.86 | EDNRB (0.76) | EDNRBEDNRA | |
| SCHEMBL6642782 | 0.86 | EDNRB (0.76) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL6639754 | 0.86 | EDNRB (0.98) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921800-B1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL MYERS SQUIBB CO (US) | 2004-04-14 | — | — | EP | claimed |
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |
| EP-0921800-B1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL MYERS SQUIBB CO (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |