Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636555 | 0.92 | F2 (0.58) | F2PKMALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6636009 | 0.91 | F2 (0.57) | F2PKMALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8026417 | 0.89 | F2 (0.66) | F2PKMALDH1A1MAPTTP53 | |
| SCHEMBL6634784 | 0.89 | F2 (0.67) | F2PKMALDH1A1MAPTTP53 | |
| SCHEMBL6634788 | 0.88 | F2 (0.54) | F2PKMALDH1A1MAPTTP53 | |
| SCHEMBL6638607 | 0.84 | F2 (0.72) | F2ALDH1A1MAPTTP53 | |
| SCHEMBL6635648 | 0.84 | F2 (0.46) | F2ALDH1A1MAPT | |
| SCHEMBL7388516 | 0.84 | F2 (0.67) | F2PKMALDH1A1MAPTTP53 | |
| SCHEMBL6634047 | 0.83 | F2 (0.58) | F2PKMALDH1A1MAPTTP53 | |
| SCHEMBL6635424 | 0.82 | F2 (0.47) | F2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6121308-A | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBONYLMETHYL) -QUINOLINE-8-SULPHONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM KG (DE) | 2000-09-19 | — | — | US | disclosed |