Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.62 |
| ▸ | FNTB | P49356 | 13/20 | 0.62 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613663 | 1.00 | FNTA (0.62) | FNTAFNTBGPR142MAPK3MAPK1 | |
| SCHEMBL6637321 | 0.94 | FNTA (0.56) | FNTAFNTBPSEN1PSEN2APH1B | |
| SCHEMBL6637318 | 0.94 | FNTA (0.56) | FNTAFNTBPSEN1PSEN2APH1B | |
| SCHEMBL6613881 | 0.89 | FNTA (0.64) | FNTAFNTBMAPK1PDE3BPDE3A | |
| SCHEMBL6633343 | 0.83 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL6614995 | 0.83 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL6633509 | 0.83 | PSEN1 (0.45) | FNTAFNTBPSEN1PSEN2APH1B | |
| SCHEMBL6633504 | 0.83 | PSEN1 (0.45) | FNTAFNTBPSEN1PSEN2APH1B | |
| SCHEMBL6617952 | 0.82 | FNTA (0.46) | FNTAFNTBGPR142MAPK3MAPK1 | |
| SCHEMBL6635231 | 0.81 | CA1 (0.42) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |