Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.47 |
| ▸ | XIAP | P98170 | 2/20 | 0.45 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664013 | 1.00 | ELANE (0.47) | ELANEXIAPMLXCMA1TAAR1 | |
| SCHEMBL1506410 | 0.94 | ELANE (0.45) | ELANEXIAPMLXCMA1 | |
| SCHEMBL1506412 | 0.94 | ELANE (0.45) | ELANEXIAPMLXCMA1 | |
| SCHEMBL29411313 | 0.92 | ELANE (0.44) | ELANEXIAPMLXCMA1TAAR1 | |
| SCHEMBL1404295 | 0.92 | ACE (0.41) | ELANEXIAPMLXCMA1ACE | |
| SCHEMBL23229944 | 0.92 | ACE (0.41) | ELANEXIAPMLXCMA1ACE | |
| SCHEMBL1404290 | 0.92 | ACE (0.41) | ELANEXIAPMLXCMA1ACE | |
| SCHEMBL1371146 | 0.92 | ELANE (0.42) | ELANEXIAPMLXCMA1ACE | |
| SCHEMBL1371152 | 0.92 | ELANE (0.42) | ELANEXIAPMLXCMA1ACE | |
| SCHEMBL29411315 | 0.90 | XIAP (0.42) | ELANEXIAPMLXCMA1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9078958-B2 | Depot stent comprising an elastin-based copolymer | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-20140363563-A1 | ELASTIN-BASED COPOLYMERS | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140356519-A1 | ELASTIN-BASED COPOLYMERS AND METHOD OF USING | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2014-12-04 | — | — | US | disclosed |
| US-8778376-B2 | Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20120263759-A1 | Coating Comprising An Elastin-Based Copolymer | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20120046640-A1 | Coating Comprising An Elastin-Based Copolymer | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2012-02-23 | — | — | US | disclosed |
| US-8029816-B2 | Medical device coated with a coating containing elastin pentapeptide VGVPG | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-20080038310-A1 | Coating comprising an elastin-based copolymer | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2008-02-14 | — | — | US | disclosed |
| WO-2007146228-A2 | ELASTIN-BASED COPOLYMERS | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070286885-A1 | Elastin-based copolymers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2007-12-13 | — | — | US | disclosed |