SCHEMBL6640563

CC(C(=O)N(C)CCc1ccncc1)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O.C[C@@H](C(=O)N(C)Cc1ccccn1)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

nearest known ligand 0.75

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	20/20	0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5223696	0.93	F10 (0.86)	F10
SCHEMBL5227220	0.92	F10 (0.78)	F10
SCHEMBL5226287	0.91	F10 (0.86)	F10
SCHEMBL5226485	0.88	F10 (0.78)	F10
SCHEMBL5228058	0.88	F10 (0.85)	F10
SCHEMBL5227735	0.86	F10 (0.81)	F10
SCHEMBL5226583	0.86	F10 (1.00)	F10
SCHEMBL5225881	0.86	F10 (1.00)	F10
SCHEMBL5421597	0.84	F10 (0.84)	F10
SCHEMBL5223534	0.84	F10 (0.84)	F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1444201-A1	2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS	GLAXO GROUP LIMITED (GB)	2004-08-11	—	—	EP	disclosed
WO-2003043981-A1	2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS	GLAXO GROUP LIMITED (GB)	2003-05-30	—	—	WO	disclosed