Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244227 | 0.91 | ATM (0.42) | P2RY1MAPTATMNPC1RAB9A | |
| SCHEMBL6637969 | 0.89 | P2RY1 (0.41) | P2RY1MAPTATML3MBTL1NPC1 | |
| SCHEMBL14639177 | 0.89 | P2RY1 (0.43) | P2RY1MAPTATML3MBTL1TDP1 | |
| SCHEMBL6637992 | 0.85 | KMT2A (0.47) | P2RY1MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL6637735 | 0.85 | P2RY1 (0.40) | P2RY1MAPTATML3MBTL1TDP1 | |
| SCHEMBL21086833 | 0.82 | P2RY1 (0.43) | P2RY1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL5593231 | 0.82 | CARM1 (0.43) | P2RY1MAPTNPC1CARM1LMNA | |
| SCHEMBL21086831 | 0.82 | P2RY1 (0.43) | P2RY1MAPTL3MBTL1LMNA | |
| SCHEMBL21307683 | 0.81 | P2RY1 (0.41) | P2RY1MAPTL3MBTL1NLRP3LMNA | |
| SCHEMBL21307577 | 0.80 | NPC1 (0.40) | P2RY1NPC1RAB9ANLRP3CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6537948-B1 | Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1122244-A1 | Uracil compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-08 | — | — | EP | disclosed |