Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778510 | 0.95 | GNRHR (1.00) | GNRHRKCNH2 | |
| SCHEMBL4052495 | 0.93 | GNRHR (0.86) | GNRHRKCNH2 | |
| SCHEMBL780206 | 0.92 | GNRHR (0.85) | GNRHRKCNH2 | |
| SCHEMBL779953 | 0.92 | GNRHR (0.85) | GNRHRKCNH2 | |
| Sufugolix SCHEMBL209021 | 0.92 | GNRHR (1.00) | GNRHR | |
| SCHEMBL779375 | 0.92 | GNRHR (0.84) | GNRHRKCNH2 | |
| SCHEMBL4885456 | 0.92 | GNRHR (0.86) | GNRHRKCNH2 | |
| SCHEMBL780527 | 0.91 | GNRHR (1.00) | GNRHRKCNH2 | |
| Sufugolix SCHEMBL4251869 | 0.91 | GNRHR (0.99) | GNRHR | |
| SCHEMBL779980 | 0.91 | GNRHR (1.00) | GNRHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163244-B1 | THIENOPYRIMIDINE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6340686-B1 | GONADOTROPIN-RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| US-6297379-B1 | GONADOTROPIN RELEASING HORMONE (GNRH, SOMETIMES CALLED LH-RH (LUTEINIZING HORMONE RELEASING HORMONE)) ANTAGONIZING ACTIVITY, TREATING SEX HORMONE-DEPENDENT DISEASES. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-02 | — | — | US | disclosed |