Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.65 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644089 | 0.96 | PDE5A (0.66) | PDE5APDE3BPDE3A | |
| SCHEMBL6646590 | 0.95 | PDE5A (0.65) | PDE5APDE3BPDE3A | |
| SCHEMBL6645498 | 0.93 | PDE5A (0.74) | PDE5APDE3BPDE3A | |
| SCHEMBL6643436 | 0.92 | PDE5A (0.66) | PDE5APDE3BPDE3A | |
| SCHEMBL6640125 | 0.91 | PDE5A (0.66) | PDE5A | |
| SCHEMBL6646009 | 0.91 | PDE5A (0.65) | PDE5APDE3BPDE3A | |
| SCHEMBL6643348 | 0.91 | PDE5A (0.63) | PDE5APDE3BPDE3A | |
| SCHEMBL6641694 | 0.88 | PDE5A (0.66) | PDE5APDE3BPDE3A | |
| SCHEMBL6646132 | 0.87 | PDE5A (0.75) | PDE5APDE3BPDE3A | |
| SCHEMBL6643613 | 0.87 | PDE5A (0.65) | PDE5APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |