Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486240 | 0.98 | PDE5A (0.82) | PDE5A | |
| Hydrochloric Acid SCHEMBL6644508 | 0.97 | PDE5A (0.81) | PDE5A | |
| SCHEMBL6642426 | 0.96 | PDE5A (0.81) | PDE5A | |
| SCHEMBL6643287 | 0.95 | PDE5A (0.78) | PDE5A | |
| SCHEMBL6484518 | 0.95 | PDE5A (0.80) | PDE5A | |
| SCHEMBL6485807 | 0.94 | PDE5A (0.81) | PDE5A | |
| Hydrochloric Acid SCHEMBL6641001 | 0.94 | PDE5A (0.79) | PDE5A | |
| Hydrochloric Acid SCHEMBL6643166 | 0.94 | PDE5A (0.80) | PDE5A | |
| SCHEMBL6643982 | 0.93 | PDE5A (0.81) | PDE5A | |
| Hydrochloric Acid SCHEMBL6641691 | 0.92 | PDE5A (0.80) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |