⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628619 | 0.96 | — | — | |
| SCHEMBL7871120 | 0.96 | — | — | |
| SCHEMBL628620 | 0.96 | — | — | |
| SCHEMBL7870235 | 0.95 | — | — | |
| SCHEMBL7870238 | 0.95 | — | — | |
| SCHEMBL6626681 | 0.94 | — | — | |
| SCHEMBL629728 | 0.94 | FNTA (0.69) | — | |
| SCHEMBL7868987 | 0.94 | — | — | |
| SCHEMBL629727 | 0.94 | FNTA (0.69) | — | |
| SCHEMBL628920 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | claimed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | claimed |