Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919815 | 0.91 | CHEK2 (0.71) | CHEK2 | |
| SCHEMBL3922054 | 0.89 | CHEK2 (0.68) | CHEK2RHEB | |
| SCHEMBL3915285 | 0.88 | CHEK2 (0.71) | CHEK2 | |
| SCHEMBL3916748 | 0.87 | CHEK2 (0.82) | CHEK2 | |
| SCHEMBL3925875 | 0.86 | CHEK2 (0.73) | CHEK2 | |
| SCHEMBL3916858 | 0.85 | CHEK2 (0.70) | CHEK2 | |
| SCHEMBL3916411 | 0.85 | CHEK2 (0.82) | CHEK2 | |
| SCHEMBL1662758 | 0.83 | CHEK2 (0.76) | CHEK2 | |
| SCHEMBL3916733 | 0.83 | CHEK2 (0.71) | CHEK2 | |
| SCHEMBL3919712 | 0.82 | CHEK2 (0.67) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435947-A1 | 2-PHENYL BENZIMIDAZOLES AND IMIDAZO-[4,5]-PYRIDINES AS CDS1/CHK2-INHIBITORS AND ADJUVANTS TO CHEMOTHERAPY OR RADIATION THERAPY IN THE TREATMENT OF CANCER | Ortho-McNeil Pharmaceutical, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003032984-A1 | 2-PHENYL BENZIMIDAZOLES AND IMIDAZO-[4,5]-PYRIDINES AS CDSI/CHK2-INHIBITORS AND ADJUVANTS TO CHEMOTHERAPY OR RADIATION THERAPY IN THE TREATMENT OF CANCER | ORTHO-MCNEIL PHARMACEUTICAL,INC. (US) | 2003-04-24 | — | — | WO | disclosed |