SCHEMBL6646294

SCHEMBL6646294

CSCCC(NC(=O)c1ccc(CN(C)C(C)(C)Cc2ccccc2)cc1-c1ccccc1C)C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.64
FNTB P49356 4/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6627088 1.00 FNTA (0.64) FNTAFNTB
SCHEMBL7874211 0.99 FNTA (0.63) FNTAFNTB
SCHEMBL7874208 0.99 FNTA (0.63) FNTAFNTB
Lithium Ion SCHEMBL7874207 0.93 FNTA (0.59) FNTAFNTB
SCHEMBL6625678 0.87 FNTA (0.78) FNTAFNTB
SCHEMBL628933 0.86 FNTA (0.71) FNTAFNTB
SCHEMBL628945 0.86 FNTA (0.71) FNTAFNTB
SCHEMBL628416 0.86 FNTA (0.70) FNTAFNTB
SCHEMBL628417 0.86 FNTA (0.70) FNTAFNTB
SCHEMBL10192971 0.84 FNTA (0.71) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986384-A4 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2004-09-15 EP claimed
EP-0986384-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 2000-03-22 EP claimed