SCHEMBL6646847

SCHEMBL6646847

CCNC(=O)Nc1ccc(-c2sc3c(c2CN(C)CCC(=O)O)c(=O)n(-c2ccccc2)c(=O)n3Cc2c(F)cccc2F)cc1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4053402 0.97 GNRHR (0.82) GNRHR
SCHEMBL4059483 0.95 GNRHR (0.82) GNRHR
SCHEMBL4051388 0.95 GNRHR (0.81) GNRHR
SCHEMBL4052003 0.94 GNRHR (0.85) GNRHR
SCHEMBL4053610 0.94 GNRHR (0.80) GNRHR
SCHEMBL4053272 0.94 GNRHR (0.94) GNRHR
SCHEMBL4056437 0.94 GNRHR (0.87) GNRHR
SCHEMBL4054195 0.93 GNRHR (0.79) GNRHR
SCHEMBL4061475 0.93 GNRHR (0.83) GNRHR
SCHEMBL4051470 0.93 GNRHR (0.78) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569570-B2 Thienopyrimidines, process for preparing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-08-04 US disclosed
US-7569570-B2 Thienopyrimidines, process for preparing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-08-04 US disclosed
EP-1479684-A1 THIENOPYRIMIDINES, PROCESS FOR PREPARING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-11-24 EP disclosed