Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646350 | 1.00 | DPP4 (0.52) | DPP4MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL6453967 | 0.85 | HPGD (0.53) | DPP4MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL6464563 | 0.85 | HPGD (0.50) | DPP4MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL8508142 | 0.85 | HPGD (0.53) | DPP4MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL14661808 | 0.85 | HPGD (0.53) | DPP4MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL20722377 | 0.84 | HPGD (0.60) | DPP4KMT2AHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL21704253 | 0.84 | HPGD (0.60) | DPP4KMT2AHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL6456086 | 0.83 | POLB (0.46) | DPP4MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL14662667 | 0.82 | HPGD (0.51) | DPP4MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL3867596 | 0.81 | POLB (0.49) | DPP4MEN1KMT2AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401830-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | disclosed |