Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 3/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6585797 | 0.99 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| Sulfuric Acid SCHEMBL2591956 | 0.97 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| Sulfuric Acid SCHEMBL7147964 | 0.94 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL12126973 | 0.94 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3103487 | 0.93 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13104217 | 0.90 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14001703 | 0.87 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| Sulfuric Acid SCHEMBL6649372 | 0.86 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| Sulfuric Acid SCHEMBL5573388 | 0.84 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| Sulfuric Acid SCHEMBL2594113 | 0.82 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699533-B2 | A CHROMONIC QUATERNARY AMMONIUM COMPOUND WITH HETEROCYCLIC RING COVALENTLY ATTACHED TO A TRIAZINE RING WITH TWO BENZENE RINGS WHICH POSSESES ATLEAST TWO CARBOXY OR SULFONIC OR PHOSPHONIC GROUPS, A PRE-TILT ADDITIVE, A CROSS-LINKING AGENT | 3M INNOVATIVE PROPERTIES COMPANY | 2004-03-02 | — | — | US | claimed |
| EP-1340120-A1 | STABILIZED LIQUID CRYSTAL ALIGNMENT STRUCTURE WITH PRE-TILT ANGLE AND DISPLAY DEVICES CONTAINING THE SAME | 3M Innovative Properties Company (US) | 2003-09-03 | — | — | EP | claimed |
| US-6524665-B2 | Useful in a liquid crystal display device c | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-25 | — | — | US | claimed |
| US-20020132065-A1 | Liquid crystal alignment structures and optical devices containing same | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-19 | — | — | US | claimed |
| EP-1232414-A1 | LIQUID CRYSTAL ALIGNMENT STRUCTURES AND OPTICAL DEVICES CONTAINING SAME | 3M Innovative Properties Company (US) | 2002-08-21 | — | — | EP | claimed |
| WO-2002044802-A1 | STABILIZED LIQUID CRYSTAL ALIGNMENT STRUCTURE WITH PRE-TILT ANGLE AND DISPLAY DEVICES CONTAINING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-06 | — | — | WO | claimed |
| US-20020066885-A1 | Stabilized liquid crystal alignment structure with pre-tilt angle and display devices containing the same | 3M INNOVATIVE PROPERTIES COMPANY | 2002-06-06 | — | — | US | claimed |
| US-6395354-B1 | SUBSTRATE OVERCOATED WITH LIQUID CRYSTAL | 3M INNOVATIVE PROPERTIES COMPANY | 2002-05-28 | — | — | US | claimed |
| WO-2001037038-A1 | LIQUID CRYSTAL ALIGNMENT STRUCTURE AND DISPLAY DEVICES CONTAINING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-05-25 | — | — | WO | claimed |
| WO-2001035161-A1 | LIQUID CRYSTAL ALIGNMENT STRUCTURES AND OPTICAL DEVICES CONTAINING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| US-6699533-B2 | A CHROMONIC QUATERNARY AMMONIUM COMPOUND WITH HETEROCYCLIC RING COVALENTLY ATTACHED TO A TRIAZINE RING WITH TWO BENZENE RINGS WHICH POSSESES ATLEAST TWO CARBOXY OR SULFONIC OR PHOSPHONIC GROUPS, A PRE-TILT ADDITIVE, A CROSS-LINKING AGENT | 3M INNOVATIVE PROPERTIES COMPANY | 2004-03-02 | — | — | US | disclosed |
| EP-1232414-B1 | LIQUID CRYSTAL ALIGNMENT STRUCTURES, METHOD OF MAKING THE SAME, AND OPTICAL DEVICES CONTAINING THE SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2004-02-04 | — | — | EP | disclosed |
| US-6645578-B2 | Substrate with an oriented layer of a zwitterionic dianiline triazine compound | 3M INNOVATIVE PROPERTIES COMPANY | 2003-11-11 | — | — | US | disclosed |
| US-20030071243-A1 | Liquid crystal materials and alignment structures and optical devices containing same | 3M INNOVATIVE PROPERTIES COMPANY | 2003-04-17 | — | — | US | disclosed |
| US-6524665-B2 | Useful in a liquid crystal display device c | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-25 | — | — | US | disclosed |
| EP-1232414-A1 | LIQUID CRYSTAL ALIGNMENT STRUCTURES AND OPTICAL DEVICES CONTAINING SAME | 3M Innovative Properties Company (US) | 2002-08-21 | — | — | EP | disclosed |
| US-20020066885-A1 | Stabilized liquid crystal alignment structure with pre-tilt angle and display devices containing the same | 3M INNOVATIVE PROPERTIES COMPANY | 2002-06-06 | — | — | US | disclosed |
| US-6395354-B1 | SUBSTRATE OVERCOATED WITH LIQUID CRYSTAL | 3M INNOVATIVE PROPERTIES COMPANY | 2002-05-28 | — | — | US | disclosed |
| WO-2001037038-A1 | LIQUID CRYSTAL ALIGNMENT STRUCTURE AND DISPLAY DEVICES CONTAINING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001035161-A1 | LIQUID CRYSTAL ALIGNMENT STRUCTURES AND OPTICAL DEVICES CONTAINING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-05-17 | — | — | WO | disclosed |