⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489846 | 1.00 | — | — | |
| SCHEMBL2385205 | 0.93 | CYP1A2 (0.62) | — | |
| SCHEMBL2980494 | 0.87 | CYP1A2 (0.50) | — | |
| SCHEMBL12306772 | 0.82 | — | — | |
| SCHEMBL21232427 | 0.82 | — | — | |
| SCHEMBL19376421 | 0.81 | CYP1A2 (0.57) | — | |
| SCHEMBL1427708 | 0.81 | — | — | |
| SCHEMBL2879971 | 0.81 | — | — | |
| SCHEMBL1428206 | 0.81 | — | — | |
| SCHEMBL3423768 | 0.81 | CYP1A2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478645-A2 | QUINOLINONE DERIVATIVES FOR TREATING CELL PROLIFERATION RELATED DISORDERS | Amgen Inc. (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003066630-A2 | QUINOLINONE DERIVATIVES FOR TREATING CELL PROLIFERATION RELATED DISORDERS | AMGEN INC. (US) | 2003-08-14 | — | — | WO | claimed |