Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.59 |
| ▸ | CCR3 | P51677 | 20/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.59 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651080 | 0.80 | HRH1 (0.66) | HRH1CCR3KCNH2CCR1 | |
| SCHEMBL2912611 | 0.78 | HRH1 (0.74) | HRH1CCR3KCNH2CCR1 | |
| SCHEMBL2919568 | 0.78 | HRH1 (0.81) | HRH1CCR3KCNH2CCR1 | |
| SCHEMBL1928120 | 0.78 | HRH1 (0.67) | HRH1CCR3KCNH2 | |
| SCHEMBL1929997 | 0.77 | HRH1 (0.70) | HRH1CCR3KCNH2CCR1 | |
| SCHEMBL1929992 | 0.76 | HRH1 (0.59) | HRH1CCR3KCNH2 | |
| SCHEMBL1930131 | 0.76 | HRH1 (0.59) | HRH1CCR3KCNH2 | |
| SCHEMBL6129272 | 0.76 | HRH1 (0.75) | HRH1CCR3KCNH2CCR1 | |
| SCHEMBL2922697 | 0.76 | HRH1 (0.75) | HRH1CCR3KCNH2CCR1 | |
| SCHEMBL2918321 | 0.75 | HRH1 (0.74) | HRH1CCR3KCNH2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478624-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003068743-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-21 | — | — | WO | disclosed |