Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 15/20 | 0.45 |
| ▸ | CCR3 | P51677 | 15/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285920 | 1.00 | HRH1 (0.45) | HRH1CCR3KCNH2DRD2DRD4 | |
| SCHEMBL3282566 | 0.91 | HRH1 (0.43) | HRH1CCR3KCNH2DRD2DRD4 | |
| SCHEMBL3282560 | 0.91 | HRH1 (0.43) | HRH1CCR3KCNH2DRD2DRD4 | |
| SCHEMBL3302154 | 0.89 | HRH1 (0.44) | HRH1CCR3KCNH2 | |
| SCHEMBL3282745 | 0.86 | HRH1 (0.42) | HRH1CCR3KCNH2DRD2 | |
| SCHEMBL3282749 | 0.86 | HRH1 (0.42) | HRH1CCR3KCNH2DRD2 | |
| SCHEMBL1929589 | 0.84 | HRH1 (0.50) | HRH1CCR3KCNH2DRD2DRD4 | |
| SCHEMBL3283811 | 0.83 | HRH1 (0.60) | HRH1CCR3KCNH2DRD2DRD4 | |
| SCHEMBL3283807 | 0.83 | HRH1 (0.60) | HRH1CCR3KCNH2DRD2DRD4 | |
| SCHEMBL1929113 | 0.81 | CCR3 (0.54) | HRH1CCR3KCNH2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478624-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003068743-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-21 | — | — | WO | disclosed |