Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6842081 | 0.99 | TYMS (0.70) | TYMS | |
| SCHEMBL6649272 | 0.83 | TYMS (1.00) | TYMS | |
| SCHEMBL6650576 | 0.81 | TYMS (1.00) | TYMS | |
| SCHEMBL6648029 | 0.81 | TYMS (0.72) | TYMS | |
| SCHEMBL6651743 | 0.81 | TYMS (1.00) | TYMS | |
| SCHEMBL6648263 | 0.74 | TYMS (1.00) | TYMS | |
| SCHEMBL6652286 | 0.72 | TYMS (1.00) | TYMS | |
| SCHEMBL4739962 | 0.72 | TYMS (0.82) | TYMS | |
| Hydrochloric Acid SCHEMBL6844303 | 0.72 | TYMS (0.98) | TYMS | |
| Hydrochloric Acid SCHEMBL6648356 | 0.72 | TYMS (0.80) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1199307-B1 | Pharmaceutically active benzoquinazoline compounds | WELLCOME FOUND (GB) | 2004-02-25 | — | — | EP | disclosed |
| EP-1199307-A1 | Pharmaceutically active benzoquinazoline compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 2002-04-24 | — | — | EP | disclosed |