Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 9/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846370 | 0.89 | TSHR (0.42) | SMPD1TSHRTHRBGGPS1MEN1 | |
| SCHEMBL16705983 | 0.89 | TSHR (0.42) | SMPD1TSHRTHRBGGPS1MEN1 | |
| Bromide SCHEMBL7764541 | 0.85 | SMPD1 (0.39) | SMPD1TSHRTHRBGGPS1MEN1 | |
| Ether SCHEMBL7496783 | 0.83 | SMPD1 (0.38) | SMPD1TSHRTHRBGGPS1MEN1 | |
| SCHEMBL2191404 | 0.79 | TSHR (0.33) | SMPD1TSHRTHRBFDPS | |
| SCHEMBL11772569 | 0.78 | TSHR (0.32) | SMPD1TSHRTHRBGGPS1FDPS | |
| SCHEMBL11761141 | 0.73 | SMPD1 (0.38) | SMPD1TSHRTHRBMEN1KMT2A | |
| SCHEMBL27762959 | 0.73 | SMPD1 (0.39) | SMPD1TSHRGGPS1MEN1MAPT | |
| SCHEMBL1821820 | 0.73 | TSHR (0.38) | SMPD1TSHR | |
| SCHEMBL27731930 | 0.72 | TSHR (0.35) | SMPD1TSHRTHRBGGPS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425781-A1 | SILICONE RESINS AND POROUS MATERIALS PRODUCED THEREFROM | Dow Corning Corporation (US) | 2004-06-09 | — | — | EP | claimed |
| US-6596834-B2 | Silicone resins having the general formula (R1SiO3/2)x(HSiO3/2)y where R1 is an alkyl group having 8 to 24 carbon atoms; x has a value of 0.05 to 0.7; y has a value of 0.3 to 0.95 and x+y =1. The resins are used to form porous | DOW CORNING CORPORATION | 2003-07-22 | — | — | US | claimed |
| US-20030088016-A1 | Silicone resins and porous materials produced therefrom | DOW CORNING CORPORATION | 2003-05-08 | — | — | US | claimed |
| WO-2003023831-A1 | SILICONE RESINS AND POROUS MATERIALS PRODUCED THEREFROM | DOW CORNING CORPORATION (US) | 2003-03-20 | — | — | WO | claimed |
| EP-1425781-A1 | SILICONE RESINS AND POROUS MATERIALS PRODUCED THEREFROM | Dow Corning Corporation (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6596834-B2 | Silicone resins having the general formula (R1SiO3/2)x(HSiO3/2)y where R1 is an alkyl group having 8 to 24 carbon atoms; x has a value of 0.05 to 0.7; y has a value of 0.3 to 0.95 and x+y =1. The resins are used to form porous | DOW CORNING CORPORATION | 2003-07-22 | — | — | US | disclosed |
| US-20030088016-A1 | Silicone resins and porous materials produced therefrom | DOW CORNING CORPORATION | 2003-05-08 | — | — | US | disclosed |
| WO-2003023831-A1 | SILICONE RESINS AND POROUS MATERIALS PRODUCED THEREFROM | DOW CORNING CORPORATION (US) | 2003-03-20 | — | — | WO | disclosed |