Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 18/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 11/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758500 | 1.00 | CHRNA7 (0.47) | CHRNA7CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL6687078 | 0.92 | CHRNA7 (0.46) | CHRNA7CHRNB2CHRNA4KCNH2HTR3E | |
| SCHEMBL6758515 | 0.92 | CHRNA7 (0.46) | CHRNA7CHRNB2CHRNA4KCNH2HTR3E | |
| SCHEMBL6755095 | 0.87 | CHRNA7 (0.61) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL6805838 | 0.87 | CHRNA7 (0.61) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL6758226 | 0.84 | CHRNA7 (0.46) | CHRNA7CHRNB2CHRNA4KCNH2HTR3E | |
| SCHEMBL6759418 | 0.83 | CHRNA7 (0.46) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL5917958 | 0.81 | CHRNA7 (0.62) | CHRNA7HTR3EHTR3BCYP2D6HTR3A | |
| SCHEMBL6802970 | 0.81 | CHRNA7 (0.62) | CHRNA7HTR3EHTR3BCYP2D6HTR3A | |
| SCHEMBL6630638 | 0.81 | CHRNA7 (0.62) | CHRNA7HTR3EHTR3BCYP2D6HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476448-A2 | AZABICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-17 | — | — | EP | claimed |
| WO-2003070731-A2 | AZABICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | claimed |